Top Python Frameworks to Learn 2021

  • Introduction
  • Django
  •  Flask
  •  Pyramid
  • Bottle
  • Spack
  • Falcon
  • CherryPy
  • TurboGears
  • Pecan
  • Web2py
  • Aero
  • TurboMail
  • CubicWeb
  •  Sanic
  • Tornado
  • Pylons
  • Quixote
  • Muffin
  • Ray
  •  Giotto
  • Webcore
  • Bobo
  • Vibora
  • Growler
  • Conclusion




Python has helped novice developers create an array of simple to complex applications. Python frameworks are like a collection of pre-made software that automatically handles everyday tasks.

Python frameworks help developers save time and avoid redundant work. Python allows a variety of frameworks where each framework has its benefits based on the project’s needs.

Python is widely used for creating GUI applications, websites, and web apps.

Today, we will look into some of the top python frameworks that are gaining immense popularity among developers for building web applications and other projects.

  1. Django

Django is a high-level python web framework for perfectionists with deadlines that lets you build robust web applications rapidly. It is an open-source framework having immense capabilities to design complex and straightforward scalable websites. It allows developers to focus more on developing their business applications without worrying about the backends like database connections, routing etc.

  1. Flask

Flask is a microframework for Python, built on the concepts of Werkzeug and Jinja 2. With an intuitive syntax and few concepts, Flask makes it possible to create straightforward projects quickly. Flask doesn’t get in your way and lets you focus on designing web applications.

  1. Pyramid

The Pyramid web framework is a small, lightweight Python web framework that will make your development experience more enjoyable. Pyramid is a Pylons Project and is the successor to the Pylons web framework.

  1. Bottle

As a lightweight web framework for Python, Bottle allows developers to create web applications quickly. It shows no dependencies other than the standard library. It’s distributed as one file and fasts to boot up.

  1. Spack

Spack looks like an open-source clone of Ruby’s well-known package manager, gems. Spack is a package management system that installs multiple versions of software packages on the same system. It provides dependency information for each package version and allows you to switch between those using a simple command-line interface or GUI client. It offers an easy way to install different versions and applications side by side without interfering with each other.

  1. Falcon

Falcon is a bare-metal Python web API framework designed for high performance and fast development. It was built to address common pitfalls with other frameworks while achieving all of this at surprisingly fast speeds (even beating out custom hand-tuned C code in benchmarks). The main goal is to provide clean, simple and extensible APIs for HTTP that encourage the design of high-performance application backends.

  1. CherryPy

CherryPy is a pythonic, object-oriented HTTP framework. Putting a CherryPy powered web application into an isolated Python environment ensures that it can operate unconfined.

  1. TurboGears

TurboGears is a next-generation web framework for Python. It’s based on the best ideas of many frameworks with various features to make Web development faster and more enjoyable. The framework is designed to make real-world web application development faster and easier while building upon solid and established concepts like Genshi, Repoze and Routes.

  1. Pecan

Pecan is a WSGI object-dispatching web framework written in Python that emphasises flexibility, simplicity and extensibility. It is built on top of CherryPy and Pylons. Modelled after ASP MVC, it provides a lightweight framework for creating RESTful web applications.

  1. Web2py

Web2py is a full-stack Python web framework for the rapid development of fast, scalable and secure database-driven web-based applications that require no coding in JavaScript, HTML or CSS. It has been used by thousands of international companies for over four years successfully. It is released under the BSD License and is free.

  1. Aero

Aero framework is a lightweight library for building web applications in Python using the Model-View-Controller design pattern, offering an easy way to manage any data. It also provides tools to create new content and is more intuitive while keeping things organised in one place.

  1. TurboMail

TurboMail is an open-source webmail plugin for RoundCube that provides AJAX technology to its front-end and its administration backend. It’s built using the latest and most remarkable techniques, like Backbone.js, RequireJS and Font-Awesome.

  1. CubicWeb

CubicWeb is a semantic web application framework that provides a complete environment to build powerful knowledge-based applications.

  1. Sanic

Sanic is a Flask-like Python 3.5+ web server that’s written to go fast. It’s based on the work done by the fantastic folks at magicstack. Sanic supports HTTP/2 and async request handlers.

  1. Tornado

Tornado is a scalable, non-blocking web server and web framework written in Python. It was developed for use by FriendFeed. Tornado is a free and open-source version of the real-time webserver (FriendFeed).

  1. Pylons

Pylons is a lightweight web framework that allows developers to focus primarily on app architecture. It began as a better version of the already excellent Pyramid framework but has since evolved into its tool that’s used and tested in production by large websites such as,, and

  1. Quixote

Quixote is a fully-featured web application framework for Python that enables programmers and web developers to develop dynamic websites, applications and portals using the Python programming language.

  1. Muffin

Muffin is an Object-Oriented framework built on top of and TurboGears, providing developers with a simple, robust, scalable and testable API to write dynamic websites in Python.

  1. Ray

Ray is a web framework for Python which implements the actor model to help you build highly concurrent apps more easily.


AIOHTTP is a single-file web client with Asyncio support written in Python to make HTTP requests. This library can send an HTTP request and get the response back without blocking the executing thread, as it would happen, for example, when using urllib2 or python-requests.

  1. Giotto

Giotto is a full-fledged framework developed by the team behind the Open-Source web application development framework Django.

  1. Webcore

Webcore is a Python web framework developed to provide an advanced platform for developing fast and powerful web applications. It offers built-in support for many useful features for a large spectrum of applications, including but not limited to templating, extending and ORM access control.

  1. Bobo

Bobo is a lightweight and high-performance library for building web applications in Python. It’s been powering the Plone CMS since 2003, serving millions of page views every day to users worldwide.

  1. Vibora

Vibora is a Python web framework built on top of libevhtp and lua-ev. It is fast and lightweight, has a minimal code base but is very extensible.

  1. Growler

Growler is a next-generation web framework for Python. It is written with speed, ease of development and flexibility in mind— growler powers the next generation web platform Aqueduct.



Using the Python frameworks will empower your development process with performance enhancements and result in high-quality web applications.

Some of the best web frameworks for scalable enterprise apps are Web2py and Django. However, for simple APIs, Flask may be a good option. It depends on what you want.

Most companies use Django as a flexible framework that combines the capabilities of microframework, Machine Learning, and web development.

We are sure you enjoyed this list of Python Frameworks to Learn in 2021. 

You can also check out the top trending Python Libraries here <link to top python libraries blog>.

Thank you so much for reading, and see you soon in another section of our blog!